Your DNA is the blueprint of your body, influencing everything from metabolism to mental well-being. Our myDNA Comprehensive Check goes beyond standard genetic testing, offering an in-depth analysis of 111 genes and 129 SNPs across key health categories:
- Cardiovascular Health
- Metabolic Health & Weight Management
- Emotional & Psychological Wellbeing
- Nutrition & Gut Health
- Cognitive Function
- Stability & Strength
- Immune Health & Inflammation
- Hormone & Reproductive health
By taking a simple cheek swab, you’ll receive a personalised genetic profile with science-backed insights into how your unique DNA affects your health, along with actionable recommendations to help you optimise your well-being. Unlike generic tests, our myDNA Comprehensive Check is conducted by an Australian NATA-accredited laboratory. Our team of molecular biologists, data scientists, and clinicians ensures your results are accurate, reliable, and tailored to your specific genetic makeup.
Understanding Your Genetic Profile
Once you receive your results from the myDNA Comprehensive Check, you will be categorised into one of three distinct genetic profiles. Each profile reflects your genetic strengths, predispositions, and potential risks, along with targeted and actionable insights into how to mitigate any negative health outcomes.
It is important to remember that genes are not your destiny. While your genetic makeup may indicate certain predispositions, lifestyle choices such as diet, exercise, stress management, pre-existing conditions, and sleep quality play a crucial role in how these genes are expressed. This means that even if you have a higher genetic risk for a condition, making the right choices can significantly reduce or even eliminate that risk. You can read more about this here.
The purpose of this test is not just to inform you of potential vulnerabilities but to empower you with the knowledge to take proactive steps that support your health and well-being.
Let’s take a closer look at each profile:
Perfect Imperfections: You’re a Genetic Marvel!
This profile indicates that your genetic blueprint is largely favourable, with no high-impact mutations that increase the risk of severe health conditions such as Alzheimer’s, haemochromatosis, type 2 diabetes, or chronic kidney disease. However, you may still carry genetic variations that can influence specific aspects of your well-being, such as metabolic function, nutrient absorption, or cardiovascular health.
Individuals with this genetic profile may carry mutations that contribute to conditions such as:
- Lactose intolerance – studies suggest that up to 65% of the world’s population experiences some form of lactose malabsorption after childhood - if you have LCT mutations, opt for lactose-free dairy products or plant-based alternatives and consider lactase enzyme supplements if consuming dairy.
- Vitamin deficiencies (B6, B12, D) – if you have NBPF3, CBS, MTRR, MTR, or CYP2R1 mutations, support optimal levels with nutrient-dense foods (e.g., leafy greens for B6, animal-based proteins for B12, and sunlight exposure for vitamin D) or targeted supplementation if needed.
- Elevated blood pressure – if you have ACE1, AGTR1, NOS1, or PPARGC1A mutations, maintain healthy blood pressure through a balanced diet rich in potassium and magnesium, stress management techniques, and limiting sodium intake
If you're feeling great, it's a sign that your lifestyle choices are complementing your genetic strengths. Your balanced approach to nature and nurture is helping you maintain optimal health. Staying informed about your genetics ensures that you can continue making proactive choices that support long-term well-being.
Minor Tune-Up Required: Small Adjustments for Big Gains
This profile suggests one or more moderate-impact genetic mutations that may influence your health by increasing the risk of certain conditions. While these genetic markers don’t determine outcomes, they highlight areas where small, proactive changes can have a meaningful impact on your well-being. Individuals with this profile may have variations that affect metabolic function, cardiovascular health, bone strength, or mental wellness.
Individuals with this genetic profile may carry mutations that contribute to conditions such as:
- Elevated cholesterol (LDL) – if you have APOE4 or LDL mutations, lower LDL levels by incorporating heart-healthy fats (e.g., omega-3s from fish and nuts), reducing saturated fat intake, and staying active.
- Vitamin deficiencies (B12, D, folate) – approximately 1 in 4 Australian adults are deficient in vitamin D, and if you carry CYP2R1 mutations, this can be addressed with a nutrient-rich diet, sun exposure, and supplementation if necessary, particularly if dietary intake is insufficient.
- Reduced bone density (osteoporosis risk) – if you have VDR-FOK, VKORC1, or SHBG mutations, support bone health with weight-bearing exercises, sufficient calcium and vitamin D intake, and maintaining hormonal balance.
- Blood sugar imbalance – if you have TCF7L2, MTNR1B, or PPARGC1A mutations, improve metabolic health through a balanced diet (reducing refined carbs and increasing fibre) and weight management.
- Mental health predispositions (anxiety, depression, increased stress) – family history of depression or anxiety doubles the risk of these disorders in first-degree relatives, and mutations in genes like COMT, MTNR1B, and 5-HT2A may increase your need to support mental well-being through mindfulness practices, adequate sleep, and balanced neurotransmitter support (via diet and supplementation).
Proactive Care for a Resilient Future: Take Control of Your Health
This profile suggests your genetic results reveal notable markers associated with increased susceptibility to more severe health conditions. Although we know that genetics alone do not dictate outcomes, our DNA provides valuable insight into areas where lifestyle choices, early detection, and proactive interventions can significantly impact your long-term well-being.
Individuals with this genetic profile may carry mutations that contribute to conditions such as:
- Alzheimer’s Disease – if you have APOE4 mutations, research shows that you can support brain health and reduce your risk of cognitive decline with a nutrient-dense Mediterranean diet, regular cognitive training, and exercise.
- Haemochromatosis (iron overload) – if you have HFE C282Y mutations, regularly monitor your iron levels and adjust your diet to limit excess iron intake.
- Type 2 Diabetes – if you have IL-6, ADIPOQ, or TCF7L2 mutations, optimise blood sugar control through diet, exercise, and weight management.
- Cardiovascular disease – if you have LPA, PPARGC1A, AGTR1, or NOS1 mutations, maintain a heart-healthy diet, engage in regular physical activity, and monitor cholesterol levels.
- Chronic kidney disease – this disease effects approximately 8-16% of the global population, and if you have GSTM1 or TNFa mutations, you can reduce your genetic risk by staying hydrated, managing blood pressure, and avoiding excessive salt and protein intake
Why Choose Our myDNA Comprehensive Check?
- Scientifically Robust: Conducted in an Australian NATA-accredited laboratory with expert data analysis.
- Actionable Insights: Personalised recommendations based on peer-reviewed genetic research. Your personalised Action Plan will provide dietary, supplement, and fitness recommendations to help you manage any genetic risks.
- Beyond Generic Testing: Unlike mainstream DNA tests, we focus on practical applications of your genetic data.
Your genes don’t define you - but understanding them empowers you to make better health decisions. Whether you’re looking to maintain, improve, or proactively manage your health, the myDNA Comprehensive Check gives you the roadmap to a healthier, more informed future.
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- Heyman MB. Lactose intolerance in infants, children, and adolescents. PEDIATRICS. 2006;118(3):1279-1286. doi:10.1542/peds.2006-1721
- Vitamin D. Australian Bureau of Statistics. https://www.abs.gov.au/articles/vitamin-d.
- Van Sprang ED, Maciejewski DF, Milaneschi Y, et al. Familial risk for depressive and anxiety disorders: associations with genetic, clinical, and psychosocial vulnerabilities. Psychological Medicine. 2020;52(4):696-706. doi:10.1017/s0033291720002299
- Agarwal P, Leurgans SE, Agrawal S, et al. Association of Mediterranean-DASH intervention for neurodegenerative delay and Mediterranean diets with Alzheimer disease pathology. Neurology. 2023;100(22). doi:10.1212/wnl.0000000000207176
- Jha V, Garcia-Garcia G, Iseki K, et al. Chronic kidney disease: global dimension and perspectives. The Lancet. 2013;382(9888):260-272. doi:10.1016/s0140-6736(13)60687-x
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