Methylation Pathways Check
$375 AUD
This test is designed as a follow up to the Genetic Methylation Check. The Methylation Pathways Check is a urine test that analyses key metabolic markers to reveal how your body manages nutrients, energy, and detoxification. Paired with the Genetic Methylation Check, this test provides a comprehensive view of your current metabolic health.
Genetic methylation testing provides valuable insights into your body’s potential by identifying variations in key genes that influence methylation. But genes are only part of the picture — they reveal your blueprint, but not necessarily how your body is functioning in real time.
The Methylation Pathways Check measures compounds in your urine which reflect the effectiveness of critical processes in your body. By analysing these metabolites or methylation pathways, you'll gain insights into your body's:
- Cellular energy production
- Detoxification efficiency
- Neurotransmitter balance
- Oxidative stress and antioxidant capacity
- Vitamin and nutrient status
- Gut health (bacterial or yeast overgrowth)
What we test
Nutritional Biomarkers
Measuring levels of these vitamins and co-factors is valuable for assessing nutritional status, identifying deficiencies, and understanding how effectively the body is using these essential nutrients. Each of these nutrients plays a critical role in a wide range of physiological processes.
This urine test measures:
Methylation Cofactors
Methylation cofactors are nutrients and compounds that play critical roles in the methylation cycle, a biochemical process essential for DNA methylation, gene expression, detoxification, neurotransmitter synthesis, and overall cellular function.
This urine test measures:
Neurotransmitter Metabolism
5HIAA is a breakdown product of serotonin, a key neurotransmitter for mood regulation, making you feel calm and at peace. Serotonin also helps regulate the gut and decreases pain sensitivity.
This urine test measures:
Oxidative Stress & DNA Damage
p-Hydroxyphenyllactate and 8-Hydroxy-2’-deoxyguanosine are markers of cell turnover and oxidative damage or liver metabolism issues
This urine test measures:
Toxin Exposure and Detoxification
Measuring these organic acids provides insights into liver detoxification efficiency and environmental toxin exposure. They can also detect oxidative damage , as well as issues in mitochondrial function.
This urine test measures:
Gut Bacterial and Yeast Imbalance
Measuring these organic acids provides critical insights into metabolic health, gut function, detoxification capacity, and microbial balance. Elevated microbial metabolites can help pinpoint bacterial or fungal overgrowth.
This urine test measures:
Oxalate Metabolites
Oxalates are produced or absorbed in the gut. Dysbiosis (imbalance of gut bacteria) can increase oxalate absorption, especially if beneficial bacteria are low. Identifying elevated oxalates can indicate the need for gut health support, such as probiotics, fibre or antimicrobials.
This urine test measures:
B-Complex Vitamins & Amino Acid Markers
B-complex vitamins and amino acid markers are crucial components that reflect the status of vitamin-dependent biochemical pathways and amino acid metabolism. These markers help in assessing nutritional status, detecting deficiencies or imbalances, and identifying potential metabolic disorders.
This urine test measures:
Citric Acid Cycle Metabolites
Abnormal levels of these metabolites can indicate issues with the citric acid cycle, such as errors of metabolism, mitochondrial dysfunction, or issues with energy production.
This urine test measures:
Carbohydrate Metabolism/ Glycolysis
Your body converts carbohydrates into glucose, then into energy. This process requires several B vitamins and lipoic acid.
This urine test measures:
Ketone/ Fatty Acid Metabolites
Your body breaks down fats for energy, a process that depends on nutrients like carnitine and vitamin B2 (riboflavin). High levels of certain fatty acid metabolites may suggest a deficiency in these nutrients – particularly carnitine.
This urine test measures:
Test instructions
You’ll receive your urine test kit in the mail, along with logistics for your sample collection.
Ready. Set. Go!
for $375