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The large intestine is packed with bacteria, whilst the small intestine typically contains very few bacteria. If the small intestine becomes overgrown with bacteria it can lead to malabsorption of key nutrients, causing symptoms such as nausea, vomiting, diarrhoea, bloating, fatigue, malabsorption of nutrients and weight loss. Small Intestinal Bacterial Overgrowth (SIBO) is also thought to be a possible factor in some cases of fibromyalgia and chronic fatigue syndrome.

What we test

SIBO Lactulose Breath Test

The lactulose test is used to measure oro-caecal transit time (OCTT) - this is the time interval between ingestion of lactulose and rise in breath hydrogen. Prolonged OCTT has been associated with SIBO.

This lactulose breath test measures:

Bacteria in the small intestine produce hydrogen and methane gas when exposed to lactulose. Hydrogen excretion is indicated by >20ppm sustained rise upon lactulose challenge.

Bacteria in the small intestine produce hydrogen and methane gas when exposed to lactulose. Methane excretion is indicated by >10ppm sustained rise upon lactulose challenge.

Normal OCTT (the time it takes for lactulose to pass through the gut) in healthy adults is approx 60-120min.

Fructose Malabsorption

Hydrogen/methane breath tests are highly specific and sensitive tools for the diagnosis of FODMAP malabsorption. They are considered first line interventions in the diagnostic workup of IBS symptoms and are recommended before dietary intervention. Breath tests avoid unnecessary food restrictions and adverse effects on gut microflora.

This breath test looks for fructose malabsorption which is advised in all IBS sufferers, especially those with symptoms related to fruit ingestion.

This represents the amount of hydrogen present in an exhaled breath a period of time after taking the fructose dose. Hydrogen is produced by microbial fermentation of carbohydrates in the gut.

Breath hydrogen is used for measurement of malabsorption where possible. If breath hydrogen production is low, further tests are conducted using equipment that also measures methane (CH4).

Test instructions

Your test kit and all instructions are posted directly to you, and there is no need to visit a collection centre.

Mail your sample back to the lab using the prepaid envelope and packaging.

Ready. Set. Go!
Buy now for $229 AUD

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This information is not intended to be a substitute for professional medical advice. Always seek the guidance of your doctor or other qualified health professional with any questions you may have regarding your health or a medical condition.
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